Details for gene set NCI_IL2-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL2-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.63146526
Normalized Enrichment Score (NES)	-1.5365051
Nominal p-value	0.010810811
FDR q-value	0.22672687
FWER p-Value	0.941

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDK2	130484 2260301 4010088 5050110	481	1.197	0.0022	No
2	E2F1	5360093	513	1.141	0.0275	No
3	PRKCZ	3780279	677	0.945	0.0410	No
4	RPS6	2060168	695	0.929	0.0620	No
5	GRB2	6650398	1188	0.612	0.0499	No
6	STAT5A	2680458	1375	0.523	0.0522	No
7	PPP2R5D	4010156 380408 5550112 5670162	1406	0.512	0.0626	No
8	CYLD	6590079	1812	0.370	0.0495	No
9	RAC1	4810687	1942	0.331	0.0503	No
10	MAPKAPK2	2850500	2120	0.284	0.0475	No
11	SGMS1	4780195	2157	0.277	0.0520	No
12	NFKB1	5420358	2177	0.270	0.0574	No
13	KRAS	2060170	2245	0.255	0.0598	No
14	RAF1	1770600	2375	0.227	0.0582	No
15	MAP2K2	4590601	2672	0.174	0.0463	No
16	UBE2D3	3190452	2980	0.131	0.0328	No
17	ARRB2	2060441	3118	0.115	0.0281	No
18	MAPK8	2640195	3135	0.114	0.0299	No
19	CHUK	7050736	3349	0.094	0.0206	No
20	NRAS	6900577	3584	0.077	0.0098	No
21	RPS6KB1	1450427 5080110 6200563	3919	0.057	-0.0069	No
22	MYC	380541 4670170	4075	0.051	-0.0141	No
23	CDK6	4920253	4077	0.051	-0.0129	No
24	MAPK1	3190193 6200253	4185	0.046	-0.0176	No
25	HRAS	1980551	4798	0.029	-0.0500	No
26	TNF	6650603	4887	0.028	-0.0541	No
27	BCL3	3990440	5383	0.020	-0.0804	No
28	CCNA2	5290075	5631	0.018	-0.0933	No
29	CALM1	380128	5743	0.017	-0.0989	No
30	HSP90AA1	4560041 5220133 2120722	6024	0.015	-0.1137	No
31	IL4	6020537	6051	0.014	-0.1148	No
32	PTPN11	2230100 2470180 6100528	7257	0.008	-0.1797	No
33	PIK3R1	4730671	7437	0.007	-0.1892	No
34	INSL3	4150092	7532	0.007	-0.1941	No
35	MAPK11	130452 3120440 3610465	7589	0.007	-0.1970	No
36	AKT1	5290746	7797	0.006	-0.2080	No
37	XPO1	540707	7981	0.005	-0.2178	No
38	PRKCE	5700053	7983	0.005	-0.2177	No
39	MAP2K1	840739	8060	0.005	-0.2217	No
40	IL2	1770725	8136	0.005	-0.2256	No
41	CALM2	6620463	8534	0.004	-0.2470	No
42	RAN	2260446 4590647	9782	0.000	-0.3144	No
43	GAB2	1410280 2340520 4280040	10726	-0.003	-0.3653	No
44	SOS1	7050338	11108	-0.004	-0.3858	No
45	JUN	840170	11404	-0.005	-0.4016	No
46	IFNG	5670592	11695	-0.006	-0.4172	No
47	MALT1	4670292	11831	-0.006	-0.4243	No
48	ATM	3610110 4050524	11982	-0.007	-0.4322	No
49	SRC	580132	12478	-0.009	-0.4588	No
50	PIK3CA	6220129	12684	-0.010	-0.4696	No
51	FBXW11	6450632	12795	-0.011	-0.4753	No
52	SYK	6940133	12885	-0.012	-0.4798	No
53	TERT	6660075	13081	-0.013	-0.4900	No
54	IRS1	1190204	13277	-0.014	-0.5002	No
55	REL	360707	13310	-0.015	-0.5016	No
56	BIRC2	2940435 4730020	13581	-0.017	-0.5158	No
57	SHC1	2900731 3170504 6520537	13907	-0.021	-0.5329	No
58	PRKCA	6400551	13942	-0.022	-0.5342	No
59	FOS	1850315	14022	-0.023	-0.5379	No
60	FRAP1	2850037 6660010	14253	-0.027	-0.5497	No
61	ERC1	1580170 2630717 6110762 6840280	14388	-0.030	-0.5562	No
62	STAM	3850008 4760441	14646	-0.036	-0.5693	No
63	FOXO3	2510484 4480451	14837	-0.044	-0.5785	No
64	NOD2	2510050	14922	-0.048	-0.5819	No
65	STAT5B	6200026	14943	-0.049	-0.5818	No
66	SP1	6590017	14989	-0.051	-0.5831	No
67	STAM2	730731 2120377	15071	-0.056	-0.5861	No
68	JAK3	70347 3290008	15166	-0.062	-0.5897	No
69	FASLG	2810044	15181	-0.063	-0.5890	No
70	RIPK2	5050072 6290632	15223	-0.066	-0.5896	No
71	IKBKG	3450092 3840377 6590592	15620	-0.102	-0.6086	No
72	LTA	1740088	15702	-0.110	-0.6104	No
73	FYN	2100468 4760520 4850687	15761	-0.116	-0.6108	No
74	PRF1	6660309	15795	-0.120	-0.6097	No
75	JAK1	5910746	15852	-0.127	-0.6098	No
76	SOCS3	5550563	16074	-0.155	-0.6181	No
77	IKBKB	6840072	16263	-0.180	-0.6240	Yes
78	ELF1	4780450	16294	-0.185	-0.6212	Yes
79	FOXP3	940707 1850692	16393	-0.203	-0.6217	Yes
80	MAPK14	5290731	16518	-0.228	-0.6231	Yes
81	BCL2	730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164	16536	-0.234	-0.6185	Yes
82	TRAF6	4810292 6200132	16620	-0.253	-0.6170	Yes
83	IL2RB	4730072	16889	-0.317	-0.6240	Yes
84	RASA1	1240315	16954	-0.335	-0.6195	Yes
85	CALM3	3390288	17028	-0.355	-0.6151	Yes
86	SOCS2	4760692	17029	-0.355	-0.6067	Yes
87	SMPD1	1410309 5550717	17184	-0.408	-0.6054	Yes
88	RELB	1400048	17205	-0.414	-0.5967	Yes
89	NFKBIA	1570152	17293	-0.450	-0.5908	Yes
90	NFKB2	2320670	17315	-0.460	-0.5811	Yes
91	RELA	3830075	17328	-0.467	-0.5707	Yes
92	MAPK3	580161 4780035	17348	-0.472	-0.5606	Yes
93	MYB	1660494 5860451 6130706	17450	-0.518	-0.5538	Yes
94	MAP3K14	5890435	17492	-0.536	-0.5434	Yes
95	LCK	3360142	17548	-0.561	-0.5331	Yes
96	BCL10	2360397	17788	-0.705	-0.5294	Yes
97	IL2RA	6620450	17824	-0.729	-0.5140	Yes
98	DOK2	5340273	17838	-0.737	-0.4974	Yes
99	IL2RG	4120273	17931	-0.809	-0.4832	Yes
100	BCL2L1	1580452 4200152 5420484	18009	-0.884	-0.4665	Yes
101	STAT3	460040 3710341	18021	-0.893	-0.4461	Yes
102	SOCS1	730139	18113	-1.004	-0.4273	Yes
103	UGCG	3420053	18140	-1.039	-0.4042	Yes
104	STAT1	6510204 6590553	18176	-1.089	-0.3803	Yes
105	CCND2	5340167	18184	-1.101	-0.3547	Yes
106	CCND3	380528 730500	18253	-1.212	-0.3298	Yes
107	TNFAIP3	2900142	18358	-1.497	-0.3001	Yes
108	CISH	840315	18365	-1.521	-0.2645	Yes
109	PTK2B	4730411	18382	-1.574	-0.2282	Yes
110	MAPK9	2060273 3780209 4070397	18430	-1.744	-0.1896	Yes
111	TNFRSF1A	1090390 6520735	18550	-2.617	-0.1343	Yes
112	RHOA	580142 5900131 5340450	18613	-5.837	0.0002	Yes